Microsoft just released the release preview guide for the scheduled Q2 2012 service update and you can download a copy here:
It details some great new features that are coming to the platform, here are my three favorites:
CRM Anywhere (Cross-Browser Support): One of the biggest headaches CRM users bring forward is that they have trouble getting it to work on Mac or that it's not supported in anything other than Internet Explorer. This release will see all that go away and open up CRM to the masses in a new way.
Official SQL Server 2012 Support: I have personally seen CRM already work on the SQL 2012 RC0 and it seems to work well right now with the exception of it connection to reporting services. Official support for SQL 2012 will be part of this release.
New CRM Mobile Client: It looks like Microsoft is getting off their butts on allowing ISV's to fill this gap in their product by releasing a new mobile client for Windows Phone 7, Android IOS, and Blackberry that will allow better access to your CRM data on those platforms and will even allow offline mode for access to data when you don't have connectivity.
There are some other features being released like social feed enhancements and such, but above are my top three.
Have great day and check out the release guide!